Acetryptine → HCID 58171320, compound

HRID 925331Notes

Reaction equation

HRID 925331 reaction equation
[NH2:1][CH2:2][CH2:3][C:4]1C2C(=CC=C(C(=O)C)C=2)N[CH:5]=1.[F:16][C:17]1[C:18](I)=[C:19]([CH:21]=[C:22]([F:25])[C:23]=1[F:24])[NH2:20]>>[F:16][C:17]1[C:23]([F:24])=[C:22]([F:25])[CH:21]=[C:19]2[C:18]=1[C:4]([CH2:3][CH2:2][NH2:1])=[CH:5][NH:20]2

Participants

3

Reactant 2

HCID 20810AcetryptineHCID 18541883HCID 18541883, compound

Product 1

HCID 58171320HCID 58171320, compound

Procedure

1-(3-(2-aminoethyl)-1H-indol-5-yl)ethanone can be prepared according to method D step II, III, IV and V starting from 3,4,5-trifluoro-2-iodoaniline.

Sources & evidence

ORD record
ord-776f2bd527474e678eaa42ac7bfccf17
Source dataset
uspto-grants-2016_03
Patent number
US09284271B2

Reaction notes

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