Toluene → HCID 57404622, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 75 mg (173 μmol) N-cyclopropyl-4-[8-(methylsulfonyl)-6-phenylimidazo[1,2-a]pyrazin-3-yl]benzamide which was prepared according to intermediate example 9-1 in 0.3 mL N,N-dimethylformamide were added 60 μL tert-butyl (5-aminopent-2-yn-1-yl)carbamate and the mixture was stirred at 50° C. overnight. Toluene was added and the mixture was evaporated. The residue was purified by chromatography to give 23.6 mg (25%) of the title compound

Provenance & Evidence