4-Fluorophenylboronic acid → HCID 73334923, compound

Participants

Reaction Steps

The title compound, off-white solid (69 mg, 87%), MS (ISP) m/z=317.0 [(M+H)+], mp 286.5° C., was prepared in accordance with the general method of example 1 from 6-bromo-7,8-difluoro-3,4-dihydro-2H-pyrazino[1,2-a]indol-1-one (intermediate 6) (75.3 mg, 0.25 mmol) and commercially available 4-fluoro-phenylboronic acid (45.5 mg, 0.325 mmol).

Provenance & Evidence