3,4-Difluorobenzeneboronic acid → HCID 73335019, compound

Participants

Reaction Steps

The title compound, white solid (46 mg, 79%), MS (ISP) m/z=313.4 [(M+H)+], mp 249.5° C., was prepared in accordance with the general method of example 1 from 6-bromo-8-methyl-3,4-dihydro-2H-pyrazino[1,2-a]indol-1-one (intermediate 10) (52 mg, 0.186 mmol) and commercially available 3,4-difluoro-phenylboronic acid (38.2 mg, 0.24 mmol).

Provenance & Evidence