(3,5-Difluorophenyl)boronic acid → HCID 73335110, compound

Participants

Reaction Steps

The title compound, white solid (69 mg, 84%), MS (ISP) m/z=331.5 [(M+H)+], mp 250° C., was prepared in accordance with the general method of example 1 from 6-bromo-8-fluoro-10-methyl-3,4-dihydro-2H-pyrazino[1,2-a]indol-1-one (intermediate 14) (74.3 mg, 0.25 mmol) and commercially available 3,5-difluoro-phenylboronic acid (51.3 mg, 0.325 mmol).

Provenance & Evidence