4-(Trifluoromethyl)phenylboronic acid → HCID 90037300, compound

Participants

Reaction Steps

The title compound, off-white solid (76 mg, 86%), MS (ISP) m/z=356.5 [(M+H)+], mp 359° C., was prepared in accordance with the general method of example 1 from 6-bromo-1-oxo-1,2,3,4-tetrahydro-pyrazino[1,2-a]indole-8-carbonitrile (intermediate 15) (72.5 mg, 0.25 mmol) and commercially available 4-trifluoromethyl-phenylboronic acid (61.7 mg, 0.325 mmol).

Provenance & Evidence