3,4-Dichlorobenzeneboronic acid → HCID 118341187, compound

Participants

Reaction Steps

The title compound, white solid (77 mg, 81%), MS (ISP) m/z=379.6 [(M+H)+], mp 240° C., was prepared in accordance with the general method of example 1 from 6-bromo-8-chloro-10-methyl-3,4-dihydro-2H-pyrazino[1,2-a]indol-1-one (intermediate 12) (78.4 mg, 0.25 mmol) and commercially available 3,4-dichloro-phenylboronic acid (62.0 mg, 0.325 mmol).

Provenance & Evidence