2-Chloropyridine-5-boronic acid → HCID 118341140, compound

Participants

Reaction Steps

The title compound, light yellow solid (49 mg, 57%), MS (ISP) m/z=346.4 [(M+H)+], mp 276° C., was prepared in accordance with the general method of example 1 from 6-bromo-8-chloro-10-methyl-3,4-dihydro-2H-pyrazino[1,2-a]indol-1-one (intermediate 12) (78.4 mg, 0.25 mmol) (78.4 mg, 0.25 mmol) and commercially available 6-chloro-pyridin-3-ylboronic acid (51.1 mg, 0.325 mmol).

Provenance & Evidence