(3,4,5-Trifluorophenyl)boronic Acid (contains varying amounts of Anhydride) → HCID 118341174, compound

Participants

Reaction Steps

The title compound, light brown solid (79 mg, 87%), MS (ISP) m/z=365.5 [(M+H)+], mp 253° C., was prepared in accordance with the general method of example 1 from 6-bromo-8-chloro-10-methyl-3,4-dihydro-2H-pyrazino[1,2-a]indol-1-one (intermediate 12) (78.4 mg, 0.25 mmol) and commercially available 3,4,5-trifluoro-phenylboronic acid (57.2 mg, 0.325 mmol).

Provenance & Evidence