(Pyrimidin-5-yl)boronic acid → HCID 73335708, compound

Participants

Reaction Steps

The title compound, off-white solid (32 mg, 41%), MS (ISP) m/z=313.5 [(M+H)+], mp 306° C., was prepared in accordance with the general method of example 1 from 6-bromo-8-chloro-10-methyl-3,4-dihydro-2H-pyrazino[1,2-a]indol-1-one (intermediate 12) (78.4 mg, 0.25 mmol) and commercially available pyrimidin-5-ylboronic acid (40.3 mg, 0.325 mmol).

Provenance & Evidence