4-(Dimethylamino)phenylboronic acid → HCID 118341137, compound

Participants

Reaction Steps

The title compound, white solid (31 mg, 37%), MS (ISP) m/z=338.5 [(M+H)+], mp 256° C., was prepared in accordance with the general method of example 1 from 6-bromo-8-fluoro-10-methyl-3,4-dihydro-2H-pyrazino[1,2-a]indol-1-one (intermediate 14) (74.3 mg, 0.25 mmol) and commercially available 4-dimethylamino-phenylboronic acid (53.6 mg, 0.325 mmol).

Provenance & Evidence