(6-Methoxypyridin-3-yl)boronic acid → HCID 118341157, compound

Participants

Reaction Steps

The title compound, off-white solid (67 mg, 82%), MS (ISP) m/z=326.4 [(M+H)+], mp 226° C., was prepared in accordance with the general method of example 1 from 6-bromo-8-fluoro-10-methyl-3,4-dihydro-2H-pyrazino[1,2-a]indol-1-one (intermediate 14) (74.3 mg, 0.25 mmol) and commercially available 6-methoxy-pyridin-3-ylboronic acid (49.7 mg, 0.325 mmol).

Provenance & Evidence