3-Fluoro-4-methylbenzeneboronic acid → HCID 118341179, compound

Participants

Reaction Steps

The title compound, light yellow solid (71 mg, 87%), MS (ISP) m/z=327.5 [(M+H)+], mp 206° C., was prepared in accordance with the general method of example 1 from 6-bromo-8-fluoro-10-methyl-3,4-dihydro-2H-pyrazino[1,2-a]indol-1-one (intermediate 14) (74.3 mg, 0.25 mmol) and commercially available 3-fluoro-4-methyl-phenylboronic acid (50.0 mg, 0.325 mmol).

Provenance & Evidence