4-Chloro-3-(trifluoromethyl)benzeneboronic acid → HCID 118341138, compound

Participants

Reaction Steps

The title compound, light yellow solid (79 mg, 80%), MS (ISP) m/z=397.4 [(M+H)+], mp 240° C., was prepared in accordance with the general method of example 1 from 6-bromo-8-fluoro-10-methyl-3,4-dihydro-2H-pyrazino[1,2-a]indol-1-one (intermediate 14) (74.3 mg, 0.25 mmol) and commercially available 4-chloro-3-trifluoromethyl-phenylboronic acid (72.9 mg, 0.325 mmol).

Provenance & Evidence