3-Pyridinylboronic acid → HCID 118341176, compound

Participants

Reaction Steps

The title compound, off-white solid (50 mg, 68%), MS (ISP) m/z=296.5 [(M+H)+], mp 239° C., was prepared in accordance with the general method of example 1 from 6-bromo-8-fluoro-10-methyl-3,4-dihydro-2H-pyrazino[1,2-a]indol-1-one (intermediate 14) (74.3 mg, 0.25 mmol) and commercially available pyridin-3-ylboronic acid (39.9 mg, 0.325 mmol).

Provenance & Evidence