(Pyrimidin-5-yl)boronic acid → HCID 73335803, compound

Participants

Reaction Steps

The title compound, light yellow solid (39 mg, 53%), MS (ISP) m/z=297.5 [(M+H)+], mp 289° C., was prepared in accordance with the general method of example 1 from 6-bromo-8-fluoro-10-methyl-3,4-dihydro-2H-pyrazino[1,2-a]indol-1-one (intermediate 14) (74.3 mg, 0.25 mmol) and commercially available pyrimidin-5-ylboronic acid (40.3 mg, 0.325 mmol).

Provenance & Evidence