6-(Dimethylamino)pyridine-3-boronic acid → HCID 73335613, compound

Participants

Reaction Steps

The title compound, grey solid (76 mg, 90%), MS (ISP) m/z=339.5 [(M+H)+], mp 259° C., was prepared in accordance with the general method of example 1 from 6-bromo-8-fluoro-10-methyl-3,4-dihydro-2H-pyrazino[1,2-a]indol-1-one (intermediate 14) (74.3 mg, 0.25 mmol) and commercially available 6-dimethylamino-pyridin-3-ylboronic acid (53.9 mg, 0.325 mmol).

Provenance & Evidence