2-Fluoropyridine-4-boronic acid → HCID 90036247, compound

Participants

Reaction Steps

The title compound, light grey solid (33 mg, 41%), MS (ISP) m/z=321.4 [(M+H)+], mp 256° C., was prepared in accordance with the general method of example 1 from 6-bromo-10-methyl-1-oxo-1,2,3,4-tetrahydro-pyrazino[1,2-a]indole-8-carbonitrile (intermediate 16) (76 mg, 0.25 mmol) and commercially available 2-fluoro-pyridin-4-ylboronic acid (45.8 mg, 0.325 mmol).

Provenance & Evidence