2-Fluoropyridine-4-boronic acid → HCID 90035973, compound

Participants

Reaction Steps

The title compound, light brown solid (59 mg, 77%), MS (ISP) m/z=307.4 [(M+H)+], mp 289° C., was prepared in accordance with the general method of example 1 from 6-bromo-1-oxo-1,2,3,4-tetrahydro-pyrazino[1,2-a]indole-8-carbonitrile (intermediate 15) (72.5 mg, 0.25 mmol) and commercially available 2-fluoro-pyridin-4-ylboronic acid (45.8 mg, 0.325 mmol).

Provenance & Evidence