2,4-Difluorophenylboronic acid → HCID 90035996, compound

Participants

Reaction Steps

The title compound, off-white solid (49 mg, 58%), MS (ISP) m/z=338.5 [(M+H)+], mp 237° C., was prepared in accordance with the general method of example 1 from 6-bromo-10-methyl-1-oxo-1,2,3,4-tetrahydro-pyrazino[1,2-a]indole-8-carbonitrile (intermediate 16) (76 mg, 0.25 mmol) and commercially available 2,4-difluoro-phenylboronic acid (51.3 mg, 0.325 mmol).

Provenance & Evidence