4-(Trifluoromethyl)phenylboronic acid → HCID 73335414, compound

Participants

Reaction Steps

The title compound, white solid (77 mg, 81%), MS (ISP) m/z=361.4 [(M+H)+], mp 276° C., was prepared in accordance with the general method of example 1 from 6-bromo-8-methoxy-3,4-dihydro-2H-pyrazino[1,2-a]indol-1-one (intermediate 18) (73.8 mg, 0.25 mmol) and commercially available 4-trifluoromethyl-phenylboronic acid (61.7 mg, 0.325 mmol).

Provenance & Evidence