(4-Chloro-2-fluorophenyl)boronic acid → HCID 90036258, compound

Participants

Reaction Steps

The title compound, white solid (83 mg, 94%), MS (ISP) m/z=354.4 [(M+H)+], mp 217.5° C., was prepared in accordance with the general method of example 1 from 7-bromo-1-oxo-2,3,4,5-tetrahydro-[1,4]diazepino[1,2-a]indole-9-carbonitrile (intermediate 20) (76.0 mg, 0.25 mmol) and commercially available 4-chloro-2-fluoro-phenylboronic acid (56.7 mg, 0.325 mmol).

Provenance & Evidence