2,4-Difluorophenylboronic acid → HCID 90036523, compound

Participants

Reaction Steps

The title compound, white solid (53 mg, 53%), MS (ISP) m/z=338.4 [(M+H)+], mp 216.5° C., was prepared in accordance with the general method of example 1 from 7-bromo-1-oxo-2,3,4,5-tetrahydro-[1,4]diazepino[1,2-a]indole-9-carbonitrile (intermediate 20) (90 mg, 0.296 mmol) and commercially available 2,4-difluoro-phenylboronic acid (60.7 mg, 0.385 mmol).

Provenance & Evidence