(Pyrimidin-5-yl)boronic acid → HCID 73335894, compound

Participants

Reaction Steps

The title compound, off-white solid (16 mg, 22%), MS (ISN) m/z=290.5 [(M+H)+], mp 323.5° C., was prepared in accordance with the general method of example 1 from 6-bromo-1-oxo-1,2,3,4-tetrahydro-pyrazino[1,2-a]indole-8-carbonitrile (intermediate 15) (72.5 mg, 0.25 mmol) and commercially available pyrimidin-5-ylboronic acid (40.3 mg, 0.325 mmol).

Provenance & Evidence