2-Chloropyridine-4-boronic acid → HCID 90035819, compound

Participants

Reaction Steps

The title compound, off-white solid (68 mg, 84%), MS (ISN) m/z=323.5 [(M+H)+], mp 286° C., was prepared in accordance with the general method of example 1 from 6-bromo-1-oxo-1,2,3,4-tetrahydro-pyrazino[1,2-a]indole-8-carbonitrile (intermediate 15) (72.5 mg, 0.25 mmol) and commercially available 2-chloro-pyridin-4-ylboronic acid (51.1 mg, 0.325 mmol).

Provenance & Evidence