4-(Hydroxymethyl)benzeneboronic acid → HCID 90036695, compound

Participants

Reaction Steps

The title compound, light brown solid (18 mg, 23%), MS (ISN) m/z=318.5 [(M+H)+], mp 257.5° C., was prepared in accordance with the general method of example 1 from 6-bromo-1-oxo-1,2,3,4-tetrahydro-pyrazino[1,2-a]indole-8-carbonitrile (intermediate 15) (72.5 mg, 0.25 mmol) and commercially available 4-hydroxymethyl-phenylboronic acid (49.4 mg, 0.325 mmol).

Provenance & Evidence