(4-Fluoro-3-methylphenyl)boronic acid → HCID 90036862, compound

Participants

Reaction Steps

The title compound, off-white solid (69 mg, 86%), MS (ISN) m/z=320.4 [(M+H)+], mp 290° C., was prepared in accordance with the general method of example 1 from 6-bromo-1-oxo-1,2,3,4-tetrahydro-pyrazino[1,2-a]indole-8-carbonitrile (intermediate 15) (72.5 mg, 0.25 mmol) and commercially available 4-fluoro-3-methyl-phenylboronic acid (50.0 mg, 0.325 mmol).

Provenance & Evidence