3-Fluoro-4-methylbenzeneboronic acid → HCID 90036802, compound

Participants

Reaction Steps

The title compound, off-white solid (72 mg, 90%), MS (ISN) m/z=320.4 [(M+H)+], mp 278.5° C., was prepared in accordance with the general method of example 1 from 6-bromo-1-oxo-1,2,3,4-tetrahydro-pyrazino[1,2-a]indole-8-carbonitrile (intermediate 15) (72.5 mg, 0.25 mmol) and commercially available 3-fluoro-4-methyl-phenylboronic acid (50.0 mg, 0.325 mmol).

Provenance & Evidence