(3,5-Difluorophenyl)boronic acid → HCID 90036042, compound

Participants

Reaction Steps

The title compound, light grey solid (65 mg, 77%), MS (ISP) m/z=338.6 [(M+H)+], mp 211° C., was prepared in accordance with the general method of example 1 from 7-bromo-1-oxo-2,3,4,5-tetrahydro-[1,4]diazepino[1,2-a]indole-9-carbonitrile (intermediate 20) (76.0 mg, 0.25 mmol) and commercially available 3,5-difluoro-phenylboronic acid (51.3 mg, 0.325 mmol).

Provenance & Evidence