4-(Trifluoromethoxy)phenylboronic acid → HCID 73335513, compound

Participants

Reaction Steps

The title compound, off-white solid (83 mg, 86%), MS (ISP) m/z=386.4 [(M+H)+], mp 230.5° C., was prepared in accordance with the general method of example 1 from 7-bromo-1-oxo-2,3,4,5-tetrahydro-[1,4]diazepino[1,2-a]indole-9-carbonitrile (intermediate 20) (76.0 mg, 0.25 mmol) and commercially available 4-trifluoromethoxy-phenylboronic acid (66.9 mg, 0.325 mmol).

Provenance & Evidence