(3,5-Difluorophenyl)boronic acid → HCID 90036076, compound

Participants

Reaction Steps

The title compound, grey solid (43 mg, 51%), MS (ISP) m/z=338.5 [(M+H)+], mp 303° C., was prepared in accordance with the general method of example 1 from 6-bromo-10-methyl-1-oxo-1,2,3,4-tetrahydro-pyrazino[1,2-a]indole-8-carbonitrile (intermediate 16) (76 mg, 0.25 mmol) and commercially available 3,5-difluoro-phenylboronic acid (51.3 mg, 0.325 mmol).

Provenance & Evidence