4-(Hydroxymethyl)benzeneboronic acid → HCID 90036084, compound

Participants

Reaction Steps

The title compound, light yellow solid (75 mg, 91%), MS (ISP) m/z=332.5 [(M+H)+], mp 256.5° C., was prepared in accordance with the general method of example 1 from 7-bromo-1-oxo-2,3,4,5-tetrahydro-[1,4]diazepino[1,2-a]indole-9-carbonitrile (intermediate 20) (76.0 mg, 0.25 mmol) and commercially available 4-hydroxymethyl-phenylboronic acid (49.4 mg, 0.325 mmol).

Provenance & Evidence