(Pyrimidin-5-yl)boronic acid → HCID 90035999, compound

Participants

Reaction Steps

The title compound, off-white solid (13 mg, 17%), MS (ISP) m/z=304.5 [(M+H)+], mp 277° C., was prepared in accordance with the general method of example 1 from 7-bromo-1-oxo-2,3,4,5-tetrahydro-[1,4]diazepino[1,2-a]indole-9-carbonitrile (intermediate 20) (76.0 mg, 0.25 mmol) and commercially available pyrimidin-5-ylboronic acid (40.3 mg, 0.325 mmol).

Provenance & Evidence