2-Chloropyridine-4-boronic acid → HCID 90036494, compound

Participants

Reaction Steps

The title compound, off-white solid (50 mg, 59%), MS (ISP) m/z=335.4 [(M+H)+], mp 281° C., was prepared in accordance with the general method of example 1 from 6-bromo-10-methyl-1-oxo-1,2,3,4-tetrahydro-pyrazino[1,2-a]indole-8-carbonitrile (intermediate 16) (76 mg, 0.25 mmol) and commercially available 2-chloro-pyridin-4-ylboronic acid (51.1 mg, 0.325 mmol).

Provenance & Evidence