(Pyrimidin-5-yl)boronic acid → HCID 90036035, compound

Participants

Reaction Steps

The title compound, off-white solid (25 mg, 33%), MS (ISN) m/z=302.4 [(M−H)+], mp 325° C., was prepared in accordance with the general method of example 1 from 6-bromo-10-methyl-1-oxo-1,2,3,4-tetrahydro-pyrazino[1,2-a]indole-8-carbonitrile (intermediate 16) (76 mg, 0.25 mmol) and commercially available pyrimidin-5-ylboronic acid (40.3 mg, 0.325 mmol).

Provenance & Evidence