(4-Fluoro-3-methylphenyl)boronic acid → HCID 90035975, compound

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Reaction Steps

The title compound, light yellow solid (73 mg, 88%), MS (ISP) m/z=334.6 [(M+H)+], mp 232° C., was prepared in accordance with the general method of example 1 from 6-bromo-10-methyl-1-oxo-1,2,3,4-tetrahydro-pyrazino[1,2-a]indole-8-carbonitrile (intermediate 16) (76 mg, 0.25 mmol) and commercially available 4-fluoro-3-methyl-phenylboronic acid (50.0 mg, 0.325 mmol).

Provenance & Evidence