(Pyrimidin-5-yl)boronic acid → HCID 73335895, compound

Participants

Reaction Steps

The title compound, light yellow solid (19 mg, 24%), MS (ISP) m/z=318.6 [(M+H)+], mp 304° C., was prepared in accordance with the general method of example 1 from 7-bromo-11-methyl-1-oxo-2,3,4,5-tetrahydro-[1,4]diazepino[1,2-a]indole-9-carbonitrile (intermediate 17) (79.5 mg, 0.25 mmol) and commercially available pyrimidin-5-ylboronic acid (40.3 mg, 0.325 mmol).

Provenance & Evidence