HRID926007

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID11355820

Methyl (1R,2S)-1-amino-2-ethenylcyclopropane-1-carboxylate

C7H11NO2

结构：C=CCCCCN(C)C(=O)[C@@H]1CC[C@@H](O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)C[C@H]1C(=O)O

HCID58282725

未命名化合物

结构：C=CCCCCN(C)C(=O)[C@@H]1CC[C@@H](O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)C[C@H]1C(=O)OC(C)(C)C

HCID58282736

未命名化合物

PRODUCTS

生成物

结构：C=CCCCCN(C)C(=O)[C@@H]1CC[C@@H](O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)C[C@H]1C(=O)N[C@]1(C(=O)OC)C[C@H]1C=C

HCID67213840

未命名化合物

PROCEDURE

实验过程

Compound 41 was synthesized from compound 40 and (1R,2S)-methyl 1-amino-2-vinylcyclopropanecarboxylate as described for compound 39 to yield compound 41 as a yellow oil in 76% yield. MS (ESI, EI+): m/z=645 (MH+)

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-4186aa642296497c85ddb637b70c8934
来源数据集: uspto-grants-2016_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US09284307B2
来源说明: uspto-grants-2016_03

反应 SMILES

[Si:1]([O:18][C@H:19]1[CH2:24][C@@H:23]([C:25](O)=[O:26])[C@H:22]([C:28](=[O:37])[N:29]([CH2:31][CH2:32][CH2:33][CH2:34][CH:35]=[CH2:36])[CH3:30])[CH2:21][CH2:20]1)([C:14]([CH3:17])([CH3:16])[CH3:15])([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH2:38][C@:39]1([C:44]([O:46][CH3:47])=[O:45])[CH2:41][C@H:40]1[CH:42]=[CH2:43].[Si](O[C@H]1C[C@@H](C(OC(C)(C)C)=O)[C@H](C(=O)N(CCCCC=C)C)CC1)(C(C)(C)C)(C1C=CC=CC=1)C1C=CC=CC=1>>[Si:1]([O:18][C@H:19]1[CH2:24][C@@H:23]([C:25]([NH:38][C@:39]2([C:44]([O:46][CH3:47])=[O:45])[CH2:41][C@H:40]2[CH:42]=[CH2:43])=[O:26])[C@H:22]([C:28](=[O:37])[N:29]([CH2:31][CH2:32][CH2:33][CH2:34][CH:35]=[CH2:36])[CH3:30])[CH2:21][CH2:20]1)([C:14]([CH3:17])([CH3:16])[CH3:15])([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1