HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 22768172, compound → Quizartinib
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 22768172 | HCID 22768172 | — |
| Reactant | 2-(4-Aminophenyl)-7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-b]-[1,3]benzothiazole | HCID 44598669 | — |
| Product | Quizartinib | HCID 24889392 | — |
Reaction Steps
reacting 7-(2-morpholin-4-yl-ethoxy)-2-(4-aminophenyl)imidazo[2,1-b]benzothiazole (VIII) with a 5-tert-butylisoxazol-3-ylcarbamate derivative (X) to yield N-(5-tert-butyl-isoxazol-3-yl)-N′-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-b][1,3]benzo-thiazol-2-yl]phenyl}urea (I); and
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09284332B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-f2d7054312ce4baeb8149cdd74c00267 |
| Source note | uspto-grants-2016_03 |