HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-ethyl 2-tert-butoxy-2-(5,7-difluoro-3-methyl-1-(trifluoromethylsulfonyloxy)naphthalen-2-yl)acetate → (S)-ethyl 2-tert-butoxy-2-(4,5,7-trifluoro-1-hydroxy-3-methylnaphthalen-2-yl)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-ethyl 2-tert-butoxy-2-(5,7-difluoro-3-methyl-1-(trifluoromethylsulfonyloxy)naphthalen-2-yl)acetate | HCID 89681775 | — |
| Reactant | (S)-ethyl 2-tert-butoxy-2-(6-chloro-4-fluoro-1-hydroxy-3-methylnaphthalen-2-yl)acetate | HCID 89681784 | — |
| Product | (S)-ethyl 2-tert-butoxy-2-(4,5,7-trifluoro-1-hydroxy-3-methylnaphthalen-2-yl)acetate | HCID 89681774 | — |
Reaction Steps
(S)-ethyl 2-tert-butoxy-2-(4,5,7-trifluoro-1-hydroxy-3-methylnaphthalen-2-yl)acetate was prepared in a similar way as (S)-ethyl 2-tert-butoxy-2-(6-chloro-4-fluoro-1-hydroxy-3-methylnaphthalen-2-yl)acetate in Example 7 except (S)-ethyl 2-tert-butoxy-2-(5,7-difluoro-3-methyl-1-(trifluoromethylsulfonyloxy)naphthalen-2-yl)acetate was used instead of (S)-ethyl 2-tert-butoxy-2-(6-chloro-1-hydroxy-3-methylnaphthalen-2-yl)acetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09284323B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-94976b177d294f1093a80faf68dfd221 |
| Source note | uspto-grants-2016_03 |