HCID 118931422, compound → HCID 118931405, compound

HRID 926376Notes

Reaction equation

HRID 926376 reaction equation
[ClH:1].N1C=CC=NC=1C(N)CC.[F:12][C:13]([F:31])([F:30])[C:14]1[N:19]=[CH:18][C:17]([C@@H:20]([NH:23][S@](C(C)(C)C)=O)[CH2:21][CH3:22])=[CH:16][N:15]=1>>[ClH:1].[F:31][C:13]([F:12])([F:30])[C:14]1[N:15]=[CH:16][C:17]([CH:20]([NH2:23])[CH2:21][CH3:22])=[CH:18][N:19]=1

Participants

3

Reactant 2

HCID 118931422HCID 118931422, compoundHCID 118946039HCID 118946039, compound

Product 1

HCID 118931405HCID 118931405, compound

Procedure

(S)-1-(2-Trifluoromethyl-pyrimidin-5-yl)-propylamine hydrochloride was obtained in analogy to comp. no. 15a from (S)-2-methyl-propane-2-sulfinic acid ((S)-1-(2-trifluoromethyl-pyrimidin-5-yl)-propyl)-amide (Comp. No. 14k).

Sources & evidence

ORD record
ord-c98fd014d0c84425a407d6f744c708b7
Source dataset
uspto-grants-2016_03
Patent number
US09284333B2

Reaction notes

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