HCID 118931422, compound → HCID 118931414, compound

HRID 926378Notes

Reaction equation

HRID 926378 reaction equation
[ClH:1].N1C=CC=NC=1C(N)CC.[F:12][C:13]([F:35])([F:34])[C:14]1[CH:19]=[C:18]([C:20]([F:23])([F:22])[F:21])[N:17]=[CH:16][C:15]=1[C@H:24]([NH:27][S@](C(C)(C)C)=O)[CH2:25][CH3:26]>>[ClH:1].[F:35][C:13]([F:12])([F:34])[C:14]1[CH:19]=[C:18]([C:20]([F:22])([F:23])[F:21])[N:17]=[CH:16][C:15]=1[CH:24]([NH2:27])[CH2:25][CH3:26]

Participants

3

Reactant 2

HCID 118931422HCID 118931422, compoundHCID 121390087HCID 121390087, compound

Product 1

HCID 118931414HCID 118931414, compound

Procedure

(R)-1-(4,6-Bis-trifluoromethyl-pyridin-3-yl)-propylamine hydrochloride was obtained in analogy to comp. no. 15a from (S)-2-methyl-propane-2-sulfinic acid [(R)-1-(4,6-bis-trifluoromethyl-pyridin-3-yl)-propyl]-amide (Comp. No. 14n). LC/MS (method 7): Rt=0.93 min; m/z=273.1 (M+H+).

Sources & evidence

ORD record
ord-8970e90ea88a436b8a9f9ebef44bd2ac
Source dataset
uspto-grants-2016_03
Patent number
US09284333B2

Reaction notes

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