HCID 118006107, compound → HCID 118006255, compound

HRID 926454Notes

Reaction equation

HRID 926454 reaction equation
[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([I:12])[CH:10]=2)[N:5]=[C:4]([O:13][CH3:14])[C:3]=1[CH2:15]C1C=CC=C(C(F)(F)F)C=1.ClC1C(C[C:38]2[CH:43]=[CH:42][CH:41]=[C:40]([C:44]([F:47])([F:46])[F:45])[CH:39]=2)=C(Cl)C2C(=CC=C(I)C=2)N=1>>[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([I:12])[CH:10]=2)[N:5]=[C:4]([O:13][CH3:14])[C:3]=1[CH2:15][C:39]1[CH:38]=[CH:43][CH:42]=[CH:41][C:40]=1[C:44]([F:47])([F:46])[F:45]

Participants

3

Reactant 2

HCID 118006107HCID 118006107, compound2×HCID 118006166HCID 118006166, compound2×

Product 1

HCID 118006255HCID 118006255, compound

Procedure

The title compound was prepared following the procedure described for the preparation of Intermediate 7: step c, substituting 2,4-dichloro-6-iodo-3-(3-(trifluoromethyl)benzyl)quinoline (Intermediate 7: step b) with 2,4-dichloro-6-iodo-3-(2-(trifluoromethyl)benzyl)quinoline (Intermediate 8: step b).

Sources & evidence

ORD record
ord-b9bd91a8da84453495c74542e6a0a5c5
Source dataset
uspto-grants-2016_03
Patent number
US09284308B2

Reaction notes

Loading…