HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Nitrobenzoyl chloride → 4-Chloro-4'-nitrobenzophenone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Nitrobenzoyl chloride | HCID 8502 | — |
| Reactant | Potassium Phosphate, Tribasic | HCID 62657 | — |
| Reactant | 4-Chlorophenylboronic acid | HCID 74299 | — |
| Catalyst | HCID 178418476 | HCID 178418476 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 4-Chloro-4'-nitrobenzophenone | HCID 347771 | — |
Reaction Steps
A mixture of (4-chlorophenyl)boronic acid (1.50 g, 9.59 mmol), 4-nitrobenzoyl chloride (1.78 g 9.59 mmol), bis(triphenylphosphine)palladium(II) chloride (0.137 g, 0.192 mmol) and K3PO4 (3.34 g, 19.2 mmol) in toluene (30 mL) was treated as described in WO 2010/015355 to provide the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09284308B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-26fc8aeaa09d48a88b9413b56d909cef |
| Source note | uspto-grants-2016_03 |