HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorobenzaldehyde → 5-(4-Fluorobenzyl)-2,2-dimethyl-1,3-dioxane-4,6-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorobenzaldehyde | HCID 68023 | — |
| Reactant | 5-(Benzo[b]thiophen-2-ylmethyl)-2,2-dimethyl-1,3-dioxane-4,6-dione | HCID 86715589 | — |
| Reactant | 2-(Benzo[b]thiophen-2-ylmethyl)malonic acid | HCID 86715590 | — |
| Product | 5-(4-Fluorobenzyl)-2,2-dimethyl-1,3-dioxane-4,6-dione | HCID 86096352 | — |
Reaction Steps
The title compound was prepared using 4-fluorobenzaldehyde in place of benzo[b]thiophene-2-carbaldehyde using the procedure described for the preparation of 5-(benzo[b]thiophen-2-ylmethyl)-2,2-dimethyl-1,3-dioxane-4,6-dione (Intermediate 39: step a).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09284308B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-41ee9a9464f1403db31f33798f849b23 |
| Source note | uspto-grants-2016_03 |