Trifluoroacetic acid → HCID 18172498, compound

Participants

Reaction Steps

A flask containing a mixture of 3-((2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-yl)methyl)benzonitrile (4.53 g, 17.5 mmol, Intermediate 70: step a) TFA (30 mL) and water (14 mL) was equipped with a reflux condenser and Drierite® at the outlet, then heated in a 65° C. oil bath for 4 hours. The mixture was concentrated and the title compound was precipitated from water and filtered.

Provenance & Evidence