HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Pyridinecarboxaldehyde → (4-fluorophenyl)(1-methyl-1H-imidazol-5-yl)methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Pyridinecarboxaldehyde | HCID 10371 | — |
| Reactant | 1-methyl-1H-imidazole-5-carbaldehyde | HCID 573592 | — |
| Reactant | HCID 178418676 | HCID 178418676 | — |
| Product | (4-fluorophenyl)(1-methyl-1H-imidazol-5-yl)methanol | HCID 66117559 | — |
Reaction Steps
The title compound was prepared analogously to the method in Intermediate 88: step a using (4-fluorophenyl)magnesium bromide and 1-methyl-1H-imidazole-5-carbaldehyde in place of (3,4-dimethoxyphenyl)magnesium bromide and nicotinaldehyde, respectively.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09284308B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-122dd108cc664d4280eca467fc97f8fc |
| Source note | uspto-grants-2016_03 |