HCID 53016961, compound → 3-Pyridinyl[4-(trifluoromethyl)phenyl]methanone

HRID 926575Notes

Reaction equation

HRID 926575 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH:7]([C:9]2[CH:14]=[CH:13][C:12]([C:15]([F:18])([F:17])[F:16])=[CH:11][CH:10]=2)[OH:8])[CH:2]=1.CN1C(C(C2C=CC=CN=2)O)=CN=C1>>[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]([C:9]2[CH:14]=[CH:13][C:12]([C:15]([F:16])([F:17])[F:18])=[CH:11][CH:10]=2)=[O:8])[CH:2]=1

Participants

3

Reactant 2

HCID 53016961HCID 53016961, compoundHCID 86715604(1-Methyl-1H-imidazol-5-yl)(pyridin-2-yl)methanol

Product 1

HCID 129300623-Pyridinyl[4-(trifluoromethyl)phenyl]methanone

Procedure

The title compound was prepared analogously to the method in Intermediate 33: step b using pyridin-3-yl(4-(trifluoromethyl)phenyl)methanol (Intermediate 91: step a) in place of (1-methyl-1H-imidazol-5-yl)(pyridin-2-yl)methanol.

Sources & evidence

ORD record
ord-96b68cafed534666909374016dcfbbbe
Source dataset
uspto-grants-2016_03
Patent number
US09284308B2

Reaction notes

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