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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 926744Generated: October 31, 2026

Ammonium Chloride → HCID 89619025, compound

https://huagongshe.com/reaction/926744

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmonium ChlorideHCID 25517—
ReactantHCID 55284823HCID 55284823—
ReactantHCID 89618873HCID 89618873—
ProductHCID 89619025HCID 89619025—

Reaction Steps

The title compound was prepared by the method similar to that mentioned in Example-6, using (R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)-4-fluoropyrazolo[1,5-a]pyridine-3-carboxylic acid and 4-amino-1-(hydroxymethyl)cyclohexanol (instead of ammonium chloride) to afford the crude compound. The crude compound was purified by Preparative TLC (using Silicagel GF254, 1000 u coated 20×20 cm dimension glass plate and 100% EtOAc as eluent) to afford 15 mg of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09289419B2
Source datasetuspto-grants-2016_03
ORD IDord-b5dcc39912794a51b24a939d35f2645a
Source noteuspto-grants-2016_03