HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonium Chloride → HCID 89619025, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonium Chloride | HCID 25517 | — |
| Reactant | HCID 55284823 | HCID 55284823 | — |
| Reactant | HCID 89618873 | HCID 89618873 | — |
| Product | HCID 89619025 | HCID 89619025 | — |
Reaction Steps
The title compound was prepared by the method similar to that mentioned in Example-6, using (R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)-4-fluoropyrazolo[1,5-a]pyridine-3-carboxylic acid and 4-amino-1-(hydroxymethyl)cyclohexanol (instead of ammonium chloride) to afford the crude compound. The crude compound was purified by Preparative TLC (using Silicagel GF254, 1000 u coated 20×20 cm dimension glass plate and 100% EtOAc as eluent) to afford 15 mg of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09289419B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-b5dcc39912794a51b24a939d35f2645a |
| Source note | uspto-grants-2016_03 |