Hydroxyamine hydrochloride → HCID 137199426, compound

Participants

Reaction Steps

To a solution of 5-(4-methanesulfonyl-benzyloxy)-pyridine-2-carbaldehyde (2.44 g, 8.4 mmol) in ethanol (1.5 mL) at 0° C. was added dropwise a solution of hydroxylamine hydrochloride (1.2 g) and NaHCO3 (1.6 g) in water (15 mL) and stirred at rt for 14 h. The reaction mixture was then filtered and the filtrate air-dried to yield 5-(4-methanesulfonyl-benzyloxy)-pyridine-2-carbaldehyde oxime (2.13 g, 83%) as a white solid.

Provenance & Evidence